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Anti-BIN2 (Polyclonal), ALEXA Fluor 594

Anti-BIN2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBIN2
SpecificityThis antibody reacts specifically with BIN2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human BIN2/BRAP1
Gene ID51411
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis, BIN1 also interacts with the transcription factors c-Myc and MyoD, BIN1 and BIN2 are BAR proteins that share 61% sequence similarity, BIN2, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region, BIN2 shows preferred expression in tissues of hematopoietic origin, In contrast to BIN1, There are two isoforms of BIN2 that are produced as a result of alternative splicing events, also known as Breast cancer-associated protein 1, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes, colon, is a 565 amino acid protein that interacts with BIN1, lymphoid and granulocytic cells, placenta, potentially functioning as a tumor suppressor, thymus, with high levels found in spleen, BAR proteins are characterized by a common N-terminal BAR (bin
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BRAP-1
Also known asBIN2 Polyclonal Antibody
Other nameAnti-BIN2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBIN2
Short nameAnti-BIN2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-BIN2 (polyclonal)
Alternative techniquepolyclonals
Identity 1053
Gene BIN2
Long gene name bridging integrator 2
Locus 12q13, 13
Discovery year 2000-05-25
GenBank acession AF146531
Entrez gene record 51411
Pubmed identfication 10903846
Classification N-BAR domain containing
Havana BLAST/BLAT OTTHUMG00000185197

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