Name : Anti-BMP5 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1788431731
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | BMP5 |
| Specificity | This antibody reacts specifically with BMP5 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Secreted |
| Antigen Source | KLH conjugated synthetic peptide derived from human BMP5 |
| Gene ID | 653 |
| Swiss Prot | P22003 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site, Jul 2008], The superfamily includes large families of growth and differentiation factors, These proteins are synthesized as prepropeptides, This gene is differentially regulated during the formation of various tumors, This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, [provided by RefSeq, and may play a potential role in glaucoma pathogenesis, and then processed into dimeric proteins, cleaved, This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | BMP5 Polyclonal Antibody |
| Other name | Anti-BMP5 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | BMP5 |
| Short name | Anti-BMP5 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-bone morphogenetic protein 5 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | BMP receptor binding, BMP5 and IDBG-91207 and ENSG00000112175 and 653, BT, Bmp5 and IDBG-185557 and ENSMUSG00000032179 and 12160, Extracellular, this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0003323 and type B pancreatic cell development and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005575 and cellular component and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007389 and pattern specification process and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010719 and negative regulation of epithelial to mesenchymal transition and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0010894 and negative regulation of steroid biosynthetic process and biological process this GO :0030539 and male genitalia development and biological process this GO :0031988 and membrane-bounded vesicle and cellular component this GO :0032348 and negative regulation of aldosterone biosynthetic process and biological process this GO :0040007 and growth and biological process this GO :0043569 and negative regulation of insulin-like growth factor receptor signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0051216 and cartilage development and biological process this GO :0070700 and BMP receptor binding and molecular function this GO :0071676 and negative regulation of mononuclear cell migration and biological process this GO :1900006 and positive regulation of dendrite development and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000065 and negative regulation of cortisol biosynthetic process and biological process this GO :2000105 and positive regulation of DNA-dependent DNA replication and biological process, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0070700: BMP receptor binding, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0070700: BMP receptor binding, 29026 and IDBG-628704 and ENSBTAG00000012870 and 507682, bone morphogenetic protein 5 |
| Identity | 1072 |
| Gene | BMP5 |
| Long gene name | bone morphogenetic protein 5 |
| Locus | 6p12, 1 |
| Discovery year | 1991-06-05 |
| Entrez gene record | 653 |
| Pubmed identfication | 1427904 11580864 |
| Classification | Endogenous ligands Bone morphogenetic proteins |
| Havana BLAST/BLAT | OTTHUMG00000014903 |