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Anti-BNIP3L (Polyclonal), ALEXA Fluor 594

Anti-BNIP3L (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBNIP3L
SpecificityThis antibody reacts specifically with BNIP3L
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human BNIP3L
Gene ID665
Swiss ProtO60238
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix, Can overcome the suppressors BCL-2 and BCL-XL, Inhibits apoptosis induced by BNIP3, Interacts with viral and cellular anti-apoptosis proteins, Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, May function as a tumor suppressor, The physical interaction of SPATA18/MIEAP, although high levels of BCL-XL expression will inhibit apoptosis, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria, Induces apoptosis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Nix BNIP3a
Also known asBNIP3L Polyclonal Antibody
Other nameAnti-BNIP3L Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBNIP3L
Short nameAnti-BNIP3L (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-B-cell CLL/lymphoma 2/adenovirus E1B 19kDa interacting protein 3-like (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BNIP3L and IDBG-13074 and ENSG00000104765 and 665, BNIP3L and IDBG-635626 and ENSBTAG00000021307 and 534615, BNIP3a and NIX, Bnip3l and IDBG-175760 and ENSMUSG00000022051 and 100043324, nuclei, protein heterodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005521 and lamin binding and molecular function this GO :0005635 and nuclear envelope and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005740 and mitochondrial envelope and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031224 and intrinsic component of membrane and cellular component this GO :0035694 and mitochondrial protein catabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051607 and defense response to virus and biological process this GO :0097345 and mitochondrial outer membrane permeabilization and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005521: lamin binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0046982: protein heterodimerization activity, this GO :0005521: lamin binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0046982: protein heterodimerization activity, 12177, 102641641, BCL2/adenovirus E1B 19kDa interacting protein 3-like
Identity 1085
Gene BNIP3L
Long gene name BCL2 interacting protein 3 like
Synonyms gene name BCL2/adenovirus E1B 19kDa interacting protein 3 like
Locus 8p21, 2
Discovery year 1997-07-01
GenBank acession AB004788
Entrez gene record 665
Pubmed identfication 9523198 9973195
RefSeq identity NM_004331
Havana BLAST/BLAT OTTHUMG00000099433

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