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Anti-BRAF35 (Polyclonal), ALEXA Fluor 594

Anti-BRAF35 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideBRAF35
SpecificityThis antibody reacts specifically with BRAF35
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human BRAF35
Gene ID10362
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A second breast cancer susceptibility gene, BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns, BRCA2, BRCA2 does not confer a substantially elevated risk of ovarian cancer, Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer, The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation, The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain, also confers a high incidence of breast cancer, but unlike BRCA1, located on chromosome 13q12-13, which associates with condensed chromatin during histone H3 phosphorylation, The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms SOXL HMGX2 BRAF35 SMARCE1r BRAF25 HMGXB2
Also known asBRAF35 Polyclonal Antibody
Other nameAnti-BRAF35 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetBRAF35
Short nameAnti-BRAF35 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-BRAF35 (polyclonal)
Alternative techniquepolyclonals
Identity 5002
Gene HMG20B
Long gene name high mobility group 20B
Synonyms gene name high-mobility group 20B
Synonyms name HMG box domain containing 2
Locus 19p13, 3
Discovery year 1999-06-11
GenBank acession BC003505
Entrez gene record 10362
Pubmed identfication 10773667
RefSeq identity NM_006339
Classification Non-canonical high mobility group
Havana BLAST/BLAT OTTHUMG00000150437

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