Name : Anti-BRCA1 Antibody
Supplier : ABBEX
Price :441
SKU : GEN2557409443
Category | Primary Antibodies |
Antibody's target | BRCA1 |
Immunogen | See techfile |
Clonality | Polyclonal |
The antibody was raised in | Rabbit |
Reactivity | Mouse, Rat, Human |
Purification | Affinity purified |
Applications | WB (for other see techfile or inquire) |
Stock availability | Shipped within 5-10 working days |
Storage conditions | Avoid repeated freeze/thaw cycles, Aliquot and store at -20 °, C |
Warnings | This product is for research use only |
Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by abbex they should be stored frozen at - 24° |
Gene target | BRCA1 |
Short name | Anti-BRCA1 Antibody |
Technique | antibodies against human proteins, antibodies for, Antibody |
Alternative name | early onset (Antibody to), antibody to-breast cancer 1 |
Alternative technique | antibodies |
Alternative to gene target | BRCA1 and IDBG-52172 and ENSG00000012048 and 672, BRCA1 and IDBG-640630 and ENSBTAG00000022520 and 353120, BRCAI and BRCC1 and BROVCA1 and IRIS and PNCA4 and PPP1R53 and PSCP and RNF53, Brca1 and IDBG-212218 and ENSMUSG00000017146 and 12189, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046600 and negative regulation of centriole replication and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050681 and androgen receptor binding and molecular function this GO :0051571 and positive regulation of histone H3-K4 methylation and biological process this GO :0051572 and negative regulation of histone H3-K4 methylation and biological process this GO :0051573 and negative regulation of histone H3-K9 methylation and biological process this GO :0051574 and positive regulation of histone H3-K9 methylation and biological process this GO :0051865 and protein autoubiquitination and biological process this GO :0070512 and positive regulation of histone H4-K20 methylation and biological process this GO :0070531 and BRCA1-A complex and cellular component this GO :0071158 and positive regulation of cell cycle arrest and biological process this GO :0071681 and cellular response to indole-3-methanol and biological process this GO :0085020 and protein K6-linked ubiquitination and biological process this GO :2000145 and regulation of cell motility and biological process this GO :2000617 and positive regulation of histone H3-K9 acetylation and biological process this GO :2000620 and positive regulation of histone H4-K16 acetylation and biological process, androgen receptor binding, early onset, nuclei, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007098 and centrosome cycle and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008274 and gamma-tubulin ring complex and cellular component this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009048 and dosage compensation by inactivation of X chromosome and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0015631 and tubulin binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030521 and androgen receptor signaling pathway and biological process this GO :0030529 and ribonucleoprotein complex and cellular component this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031436 and BRCA1-BARD1 complex and cellular component this GO :0031572 and G2 DNA damage checkpoint and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031941 and filamentous actin and cellular component this GO :0034446 and substrate adhesion-dependent cell spreading and biological process this GO :0035066 and positive regulation of histone acetylation and biological process this GO :0035067 and negative regulation of histone acetylation and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043009 and chordate embryonic development and biological process this GO :0043234 and protein complex and cellular component this GO :0043627 and response to estrogen and biological process this GO :0044030 and regulation of DNA methylation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045717 and negative regulation of fatty acid biosynthetic process and biological process this GO :0045739 and positive regulation of DNA repair and biological process this GO :0045892 and negative regulation of transcription, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000793 and condensed chromosome and cellular component this GO :0000794 and condensed nuclear chromosome and cellular component this GO :0001726 and ruffle and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0003723 and RNA binding and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005694 and chromosome and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006260 and DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006301 and postreplication repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006349 and regulation of gene expression by genetic imprinting and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006359 and regulation of transcription from RNA polymerase III promoter and biological process this GO :0006633 and fatty acid biosynthetic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006978 and DNA damage response, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003684: damaged DNA binding and also this GO :0003713: transcription coactivator activity and also this GO :0003723: RNA binding and also this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0015631: tubulin binding and also this GO :0016874: ligase activity and also this GO :0019899: enzyme binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046872: metal ion binding and also this GO :0050681: androgen receptor binding, this GO :0003684: damaged DNA binding, this GO :0003713: transcription coactivator activity, this GO :0003723: RNA binding, this GO :0004842: ubiquitin-protein transferase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0015631: tubulin binding, this GO :0016874: ligase activity, this GO :0019899: enzyme binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046872: metal ion binding, this GO :0050681: androgen receptor binding, breast cancer 1 |
Identity | 1100 |
Gene | BRCA1 |
Long gene name | BRCA1, DNA repair associated |
Synonyms gene name | breast cancer 1, early onset breast cancer 1 |
Synonyms | RNF53 BRCC1 PPP1R53 FANCS |
Synonyms name | BRCA1/BRCA2-containing complex, complementation group S , regulatory subunit 53 Fanconi anemia, subunit 1 protein phosphatase 1 |
Locus | 17q21, 31 |
Discovery year | 1991-02-20 |
GenBank acession | U14680 |
Entrez gene record | 672 |
Pubmed identfication | 1676470 25472942 |
RefSeq identity | NM_007294 |
Classification | Ring finger proteins Protein phosphatase 1 regulatory subunits BRCA1 A complex BRCA1 B complex BRCA1 C complex Fanconi anemia complementation groups |
Havana BLAST/BLAT | OTTHUMG00000157426 |
Locus Specific Databases | Breast Cancer BRCA1 database at LOVD-China LOVD - Leiden Open Variation Database LOVD - Leiden Open Variation Database LRG_292 |