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Anti-BRCC36 Antibody

Anti-BRCC36 Antibody size: 100ug 448

Supplier MBS POLYCLONALS 1
Price 448
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI BRCC36
Alternative name2RABBIT ANTI BRCC36
Alternative name3Lapin ANTI BRCC36
Alternative name4BRCC36
Alternative name5N/A
Other names BRCA1-A complex subunit BRCC36, BRCA1-A complex subunit BRCC36, BRCA1/BRCA2-containing complex, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCA1/BRCA2-containing complex subunit 36, BRISC complex subunit BRCC36, BRISC complex subunit BRCC36, Lys-63-specific deubiquitinase BRCC36, lys-63-specific deubiquitinase BRCC36, subunit 3, lys-63-specific deubiquitinase BRCC36 isoform 2
Gene nameBRCC36
Gene name synonimsN/A
Other gene names BRCC3, BRCC36, BRCC36, C6, C6, CXorf53, CXorf53, RP11-143H17, 1A, 1A, 2, BRCC3
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity BRCA2, It has been hypothesized that BRCC36 could be a potentially important target in the treatment of radiation-resistant breast tumours, Rad51 and BRCC45, _x000D__x000D_BRCC36, _x000D__x000D_Research has shown that BRCC36 is aberrantly expressed in the majority of breast tumours indicating a potential role in the pathogenesis of the disease, _x000D__x000D_Studies have demonstrated that BRCC36 functions in enhancing cellular survival following DNA damage and that it is essential for ionizing radiation induced BRCA1 phosphorylation and nuclear foci formation, a 36, forms a holoenzyme complex that possesses an ubiquitin E3 ligase activity, together with BRCA1, 7kDa nuclear protein, BRCC36 Recognises human BRCA1/BRCA2 complex subunit 36 (BRCC36)
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0mg/ml, IgG concentration 1
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: Immunohistology - Paraffin (IHC), Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetBRCC36
Short nameAnti-BRCC36 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameantibody to-BRCC36 (Antibody to)
Alternative techniqueantibodies
Identity 24185
Gene BRCC3
Long gene name BRCA1/BRCA2-containing complex subunit 3
Synonyms gene CXorf53
Synonyms gene name chromosome X open reading frame 53 BRCA1/BRCA2-containing complex, subunit 3
Synonyms C6, 1A BRCC36
Synonyms name Lys-63-specific deubiquitinase
Locus Xq28
Discovery year 2004-12-03
GenBank acession X64643
Entrez gene record 79184
Pubmed identfication 1303175 14636569
RefSeq identity NM_024332
Classification BRISC complex BRCA1 A complex
Havana BLAST/BLAT OTTHUMG00000022658

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