Anti-c-Maf (Polyclonal), ALEXA Fluor 594

Anti-c-Maf (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	c-Maf
Specificity	This antibody reacts specifically with c-Maf
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Nucleus
Antigen Source	KLH conjugated synthetic peptide derived from human c-Maf
Gene ID	4094
Swiss Prot	O75444
Applications	IF(IHC-P), FCM
Applications with corresponding dilutions	IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Activates the expression of IL4 in T helper 2 (Th2) cells, Activates transcription of the CD13 proximal promoter in endothelial cells, Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity), Binds element G1 on the glucagon promoter, Binds to the ARE sites of detoxifying enzyme gene promoters, Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters, Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter, Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression, Involved either as an oncogene or as a tumor suppressor, Involved in embryonic lens fiber cell development, Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development, Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation, Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction, Together with PAX6, When overexpressed, depending on the cell context, represses anti-oxidant response element (ARE)-mediated transcription, transactivates strongly the glucagon gene promoter through the G1 element, Acts as a transcriptional activator or repressor
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Also known as	c-Maf Polyclonal Antibody
Other name	Anti-c-Maf Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	c-Maf
Short name	Anti-c-Maf (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-c-Maf (polyclonal)
Alternative technique	polyclonals
Identity	24319
Gene	CMIP
Long gene name	c-Maf inducing protein
Locus	16q23, 2-q23, 3
Discovery year	2011-08-04
GenBank acession	AB051481
Entrez gene record	80790
Pubmed identfication	11214970 12939343
RefSeq identity	NM_030629
Havana BLAST/BLAT	OTTHUMG00000176520

Anti-c-Maf (Polyclonal), ALEXA Fluor 594

Anti-c-Maf (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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