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Anti-c-Raf (Ser259) (Polyclonal), ALEXA Fluor 594

Anti-c-Raf (Ser259) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/Peptidec-Raf Ser259
SpecificityThis antibody reacts specifically with c-Raf (Ser259)
ModificationPhosphorylation
Modification siteSer259
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Ser259
Gene ID5894
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It is part of the Ras dependent signaling pathway from receptors to the nucleus, Raf1 is involved in the transduction of mitogenic signals from the cell membrane to the nucleus, and cRaf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen activated protein kinase (MAPK) pathway, and is a signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that once activated, bRaf, cRaf kinase (also known as Raf1) is a small GTPase like kinase of 73 kDa, phosphorylates MEK which in turn phosphorylates ERK, The Raf family of serine/threonine specific kinases is comprised of three members (aRaf
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms 6430402F14Rik, AA990557, BB129353, C-RAF, Craf 1 transforming gene, Craf1, Craf1 transforming gene, D830050J10Rik, EC 2, MGC102375, Murine sarcoma 3611 oncogene 1, RAF, RAF1, Raf 1, Raf proto oncogene serine/threonine protein kinase, Raf-1, Raf1Ser259, c Raf, c-Raf, c-Raf, cRaf, murine leukemia viral v-raf-1 oncogene homolog 1 3611-MSV, proto-oncogene c-RAF, v-Raf, v-raf-1 murine leukemia viral oncogene homolog 1, vraf1 murine leukemia viral oncogene homolog 1, 1, 7, 11, RAF1phospho S259
Also known asc-Raf (Ser259) Polyclonal Antibody
Other nameAnti-c-Raf (Ser259) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetc-Raf (Ser259)
Short nameAnti-c-Raf (Ser259) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-c-Raf (Ser259) (polyclonal)
Alternative techniquepolyclonals

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