Name : Anti-C16orf57 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6141007781
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | C16orf57 |
| Specificity | This antibody reacts specifically with C16orf57 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human C16orf57 |
| Gene ID | 79650 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Another skin manifestation is pachyonychia, Bone marrow abnormalities account for neutropenia and may evolve into myelodysplasia associated with the risk of leukemic transformation, It gradually spreads centripetally and, One of the most important extracutaneous symptoms is an increased susceptibility to infections, PN is a genodermatosis characterized by poikiloderma, Poikiloderma with neutropenia shows phenotypic overlap with Rothmund-Thomson syndrome, The disorder starts as a papular erythematous rash on the limbs during the first year of life, as the papular rash resolves, but alopecia and leukoplakia are distinctively absent, hypo- and hyperpigmentation result, mainly affecting the respiratory system, pachyonychia and chronic neutropenia, primarily due to a chronic neutropenia and to neutrophil functional defects, with development of telangiectasias, Defects in C16orf57 are the cause of poikiloderma with neutropenia (PN), Involvement in disease |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ13154 HVSL1 Mpn1 |
| Also known as | C16orf57 Polyclonal Antibody |
| Other name | Anti-C16orf57 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | C16orf57 |
| Short name | Anti-C16orf57 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-C16orf57 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 25792 |
| Gene | USB1 |
| Long gene name | U6 snRNA biogenesis phosphodiesterase 1 |
| Synonyms gene | C16orf57 |
| Synonyms gene name | chromosome 16 open reading frame 57 U6 snRNA biogenesis 1 |
| Synonyms name | HVSL motif containing 1 poikiloderma with neutropenia U six biogenesis 1 mutated in poikiloderma with neutropenia protein 1 |
| Locus | 16q21 |
| Discovery year | 2006-02-17 |
| GenBank acession | AK023216 |
| Entrez gene record | 79650 |
| Pubmed identfication | 20004881 20503306 22899009 23022480 |
| RefSeq identity | NM_024598 |
| Havana BLAST/BLAT | OTTHUMG00000133456 |
| Locus Specific Databases | LRG_352 |