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Anti-C16orf57 (Polyclonal), ALEXA Fluor 594

Anti-C16orf57 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideC16orf57
SpecificityThis antibody reacts specifically with C16orf57
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human C16orf57
Gene ID79650
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Another skin manifestation is pachyonychia, Bone marrow abnormalities account for neutropenia and may evolve into myelodysplasia associated with the risk of leukemic transformation, It gradually spreads centripetally and, One of the most important extracutaneous symptoms is an increased susceptibility to infections, PN is a genodermatosis characterized by poikiloderma, Poikiloderma with neutropenia shows phenotypic overlap with Rothmund-Thomson syndrome, The disorder starts as a papular erythematous rash on the limbs during the first year of life, as the papular rash resolves, but alopecia and leukoplakia are distinctively absent, hypo- and hyperpigmentation result, mainly affecting the respiratory system, pachyonychia and chronic neutropenia, primarily due to a chronic neutropenia and to neutrophil functional defects, with development of telangiectasias, Defects in C16orf57 are the cause of poikiloderma with neutropenia (PN), Involvement in disease
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ13154 HVSL1 Mpn1
Also known asC16orf57 Polyclonal Antibody
Other nameAnti-C16orf57 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetC16orf57
Short nameAnti-C16orf57 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-C16orf57 (polyclonal)
Alternative techniquepolyclonals
Identity 25792
Gene USB1
Long gene name U6 snRNA biogenesis phosphodiesterase 1
Synonyms gene C16orf57
Synonyms gene name chromosome 16 open reading frame 57 U6 snRNA biogenesis 1
Synonyms name HVSL motif containing 1 poikiloderma with neutropenia U six biogenesis 1 mutated in poikiloderma with neutropenia protein 1
Locus 16q21
Discovery year 2006-02-17
GenBank acession AK023216
Entrez gene record 79650
Pubmed identfication 20004881 20503306 22899009 23022480
RefSeq identity NM_024598
Havana BLAST/BLAT OTTHUMG00000133456
Locus Specific Databases LRG_352

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