Name : Anti-C17orf57 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5963122498
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | C17orf57 |
| Specificity | This antibody reacts specifically with C17orf57 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human C17orf57 |
| Gene ID | 124989 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Alexander disease, BRCA1 is directly involved in DNA repair, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17, Chromosome 17 is also linked to neurofibromatosis, Chromosome 17 makes up over 2, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth, colon, namely, p53 and BRCA1, prostate gland and fallopian tubes, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, 200 genes, 5% of the human genome with about 81 million bases encoding over 1, C17orf57 is a 973 amino acid protein that is encoded by a gene mapping to human chromosome 17 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ40342 |
| Also known as | C17orf57 Polyclonal Antibody |
| Other name | Anti-C17orf57 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | C17orf57 |
| Short name | Anti-C17orf57 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-C17orf57 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 26864 |
| Gene | EFCAB13 |
| Long gene name | EF-hand calcium binding domain 13 |
| Synonyms gene | C17orf57 |
| Synonyms gene name | chromosome 17 open reading frame 57 |
| Locus | 17q21, 32 |
| Discovery year | 2005-12-20 |
| GenBank acession | BC036407 |
| Entrez gene record | 124989 |
| RefSeq identity | NM_152347 |
| Classification | EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000164767 |