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Anti-C19orf46 (Polyclonal), ALEXA Fluor 594

Anti-C19orf46 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideC19orf46
SpecificityThis antibody reacts specifically with C19orf46
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human C19orf46
Gene ID163183
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information C19orf46 contains a KASH domain, C19orf46 interacts with UKHC and KCL1, C19orf46 is encoded by a gene located on human chromosome 19, C19orf46 partcipates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome and Golgi apparatus as well as basal localization of the nucleus, and exists as two alternatively spliced isoforms, mediates nuclear enevelop targeting and binds to the SUN domain of SUN1 and SUN2, which consists of a transmembrane motif, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA, C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ36445 Nesprin-4 Nesp4
Also known asC19orf46 Polyclonal Antibody
Other nameAnti-C19orf46 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetC19orf46
Short nameAnti-C19orf46 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-C19orf46 (polyclonal)
Alternative techniquepolyclonals
Identity 26703
Gene SYNE4
Long gene name spectrin repeat containing nuclear envelope family member 4
Synonyms gene C19orf46 DFNB76
Synonyms gene name autosomal recessive 76 , chromosome 19 open reading frame 46 deafness
Locus 19q13, 12
Discovery year 2006-07-12
GenBank acession BC038360
Entrez gene record 163183
Pubmed identfication 23348741
RefSeq identity NM_001039876
Classification Spectrin repeat containing nuclear envelope family Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000048135

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