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Anti-C1s (Polyclonal), ALEXA Fluor 594

Anti-C1s (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideC1s
SpecificityThis antibody reacts specifically with C1s
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human C1s
Gene ID716
Swiss ProtP09871
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activated C1s is in the form of a disulfide-linked heterodimer consisting of a heavy chain and a light chain, Binding of these proteins to their respective G protein-coupled receptors induces proinflammatory events, C1, C1 consists of a calcium dependent trimolecular complex of C1r, C1q, C1s and C1q in a 2:2:1 ratio, C3, C4, Defects in the gene encoding for C1s can cause selective C1s deficiency, a disorder characterized by early onset of various autoimmune diseases, and C5, and cellular chemotaxis, arachidonic acid metabolism, are potent anaphylatoxins that are released during complement activation, cytokine release, leukocyte activation, smooth muscle contraction, such as cellular degranulation, the first component of the classical pathway of the serum complement system, together with proenzymes C1r and C1s, yield C1, The complement component proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asC1s Polyclonal Antibody
Other nameAnti-C1s Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetC1s
Short nameAnti-C1s (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, s subcomponent (polyclonal), antibody to-complement component 1
Alternative techniquepolyclonals
Identity 1247
Gene C1S
Long gene name complement C1s
Synonyms gene name complement component 1, s subcomponent
Locus 12p13, 31
Discovery year 2001-06-22
Entrez gene record 716
RefSeq identity NM_001734
Classification Sushi domain containing Complement system
Havana BLAST/BLAT OTTHUMG00000150305
Locus Specific Databases C1Sbase: Mutation registry for C1s deficiency LRG_25

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