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Anti-C5a anaphylatoxin (Polyclonal), ALEXA Fluor 594

Anti-C5a anaphylatoxin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideC5a anaphylatoxin
SpecificityThis antibody reacts specifically with C5a anaphylatoxin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from mouse C5a (725-770aa)
Gene ID15139
Swiss ProtP06684
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesMouse (Mus musculus)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, C5 anaphylatoxin is a mediator of local inflammatory process, C5-C9, C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation, C5b has a transient binding site for C6, Derived from proteolytic degradation of complement C5, The C5b-C6 complex is the foundation upon which the lytic complex is assembled, and histamine release from mast cells and basophilic leukocytes, contraction of smooth muscle, increased vascular permeability, into the membrane attack complex, Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CPAMD4 C5a C5b
Also known asC5a anaphylatoxin Polyclonal Antibody
Other nameAnti-C5a anaphylatoxin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetC5a anaphylatoxin
Short nameAnti-C5a anaphylatoxin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-C5a anaphylatoxin (polyclonal)
Alternative techniquepolyclonals
Identity 1331
Gene C5
Long gene name complement C5
Synonyms gene name complement component 5
Synonyms name prepro-C5 C5a anaphylatoxin
Locus 9q33, 2
Discovery year 2001-06-22
GenBank acession M57729
Entrez gene record 727
RefSeq identity NM_001735
Classification Endogenous ligands Complement system C3 and PZP like, alpha-2-macroglobulin domain containing
Havana BLAST/BLAT OTTHUMG00000020579
Locus Specific Databases C5base: Mutation registry for C5 deficiency LRG_28

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