Name : Anti-C9b/C9 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7596259835
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Complement component C9b |
| Specificity | This antibody reacts specifically with C9b/C9 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Complement component C9b |
| Gene ID | 735 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | C6, C7 and C8, C9 binds to the membrane associated C5b-8 protein, C9 is a part of the membrane attack complex (MAC), Molecules can then diffuse freely through this transmembrane channel, The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, These complement proteins bind to the outer surface of the plasma membrane of the invading cell, These polymerized C9 molecules form a ring structure in the membrane, an important component of the immune system, causing cell lysis and destruction of the invading bacterial cell, which leads to the circular polymerization of 12-18 C9 molecules, C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | Complement component C9, Complementcomponent C9b, CO9_HUMAN |
| Also known as | C9b/C9 Polyclonal Antibody |
| Other name | Anti-C9b/C9 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | C9b/C9 |
| Short name | Anti-C9b/C9 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-C9b/complement component 9 (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | ARMD15 and C9D, C9 and IDBG-128081 and ENSMUSG00000022149 and 12279, C9 and IDBG-17892 and ENSG00000113600 and 735, C9 and IDBG-629942 and ENSBTAG00000016149 and 526766, Extracellular, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0019836 and hemolysis by symbiont of host erythrocytes and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006957 and complement activation, this GO :0005515: protein binding, this GO :0005515: protein binding, complement component 9 |