Name : Anti-C9ORF46 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4365119307
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | C9ORF46 |
| Specificity | This antibody reacts specifically with C9ORF46 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human C9ORF46 |
| Gene ID | 55848 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias, Considered to play a role in gender determination, ENG, Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP, Hereditary hemorrhagic telangiectasia, Notably, The gene encoding C9orf46 maps to human chromosome 9, chromosome 9 encompasses the largest interferon family gene cluster, deletion of the distal portion of 9p can lead to development of male to female sex reversal, is associated with the chromosome 9 gene encoding endoglin protein, the phenotype of a female with a male X, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes, which is characterized by harmful vascular defects, C9orf46 is a 147 amino acid transmembrane protein, Y genotype |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | MDS030 FLJ14688 AD025 Plg-RKT |
| Also known as | C9ORF46 Polyclonal Antibody |
| Other name | Anti-C9ORF46 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | C9ORF46 |
| Short name | Anti-C9ORF46 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-C9ORF46 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 23633 |
| Gene | PLGRKT |
| Long gene name | plasminogen receptor with a C-terminal lysine |
| Synonyms gene | C9orf46 |
| Synonyms gene name | C-terminal lysine transmembrane protein , chromosome 9 open reading frame 46 plasminogen receptor |
| Synonyms name | uncharacterized hematopoietic stem/progenitor cells protein MDS030 plasminogen receptor with a C-terminal lysine |
| Locus | 9p24, 1 |
| Discovery year | 2003-11-27 |
| GenBank acession | AF225420 |
| Entrez gene record | 55848 |
| Pubmed identfication | 12477932 21940822 |
| RefSeq identity | NM_018465 |
| Havana BLAST/BLAT | OTTHUMG00000019501 |