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Anti-CABC1 (Polyclonal), ALEXA Fluor 594

Anti-CABC1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCABC1
SpecificityThis antibody reacts specifically with CABC1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human ADCK3/CABC1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CoQ10 deficiency is an autosomal recessive disorder with variable manifestations, It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, Patients can manifest brisk tendon reflexes and Hoffmann sign, Patients show progressive incoordination of gait and often poor coordination of hands, SCAR9 is an autosomal recessive form characterized by gait ataxia and cerebellar atrophy with slow progression and few associated features, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, also known as autosomal recessive cerebellar ataxia type 2 (ARCA2), an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, exercise intolerance and elevated serum lactate, mild axonal degeneration of the sural nerve, mild psychomotor retardation, speech and eye movements, Defects in ADCK3 are the cause of spinocerebellar ataxia autosomal recessive type 9 (SCAR9) [MIM:612016], Involvement in disease:Defects in ADCK3 are a cause of coenzyme Q10 deficiency (CoQ10 deficiency), May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain, Tissue specificity:Ubiquitously expressed with a relatively greater abundance in heart and skeletal muscle
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms COQ8 SCAR9
Also known asCABC1 Polyclonal Antibody
Other nameAnti-CABC1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCABC1
Short nameAnti-CABC1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CABC1 (polyclonal)
Alternative techniquepolyclonals
Identity 16812
Gene COQ8A
Long gene name coenzyme Q8A
Synonyms gene CABC1 ADCK3
Synonyms gene name ABC1 activity of bc1 complex homolog (S, ABC1 activity of bc1 complex like (S, S, chaperone-ABC1 (activity of bc1 complex, pombe) aarF domain containing kinase 3 , pombe) chaperone, pombe)-like chaperone
Synonyms name coenzyme Q8 homolog (yeast)
Locus 1q42, 13
Discovery year 2001-10-31
GenBank acession AJ278126
Entrez gene record 56997
Pubmed identfication 18319072 18319074 25498144
RefSeq identity NM_020247
Havana BLAST/BLAT OTTHUMG00000037621
Locus Specific Databases LRG_1092

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