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Anti-CALHM1/FAM26C (Polyclonal), ALEXA Fluor 594

Anti-CALHM1/FAM26C (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCALHM1/FAM26C
SpecificityThis antibody reacts specifically with CALHM1/FAM26C
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CALHM1/FAM26C
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CALHM1 co-localizes with GRP 78 to the endoplasmic reticulum, CALHM1 homomultimerizes and shares strong sequence similarities with the selectivity filter of the NMDA receptor, CALHM1 may be a pore-forming ion channel that controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration in the cell, CALHM1 may be a potential factor involved in the pathogenesis of Alzheimer's disease, It is suggested that CALHM1 regulates amyloid precursor protein proteolysis and aggregated amyloid-beta peptides levels in a Ca2+ dependent manner, Predominantly expressed in adult brain, which generates a large Ca2+ conductance across the plasma membrane, CALHM1 is a 346 amino acid multi-pass endoplasmic reticulum membrane protein that belongs to the FAM26 family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asCALHM1/FAM26C Polyclonal Antibody
Other nameAnti-CALHM1/FAM26C Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCALHM1/FAM26C
Short nameAnti-CALHM1/FAM26C (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CALHM1/FAM26C (polyclonal)
Alternative techniquepolyclonals
Identity 23494
Gene CALHM1
Long gene name calcium homeostasis modulator 1
Synonyms gene FAM26C
Synonyms gene name family with sequence similarity 26, member C
Locus 10q24, 33
Discovery year 2004-05-27
GenBank acession BC036208
Entrez gene record 255022
Pubmed identfication 18585350
RefSeq identity NM_001001412
Havana BLAST/BLAT OTTHUMG00000018991

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