Name : Anti-CAMK2D (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN6943974706
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CAMK2D |
| Specificity | This antibody reacts specifically with CAMK2D |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CAMK2D/CaMKII delta |
| Gene ID | 817 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | â, &, An additional kinase, CaMKII and CaMKIV, CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription, CaMKIV is stimulated by Ca2+ and CaM but phosphorylation by a CaMK is also required for full activation, CaMKK, Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity, There are four CaMKII isozymes designated &, and &, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177, which may or may not be co-expressed in the same tissue type, #8706, &circ, «, The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, aring, copy |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | CAMK2D Polyclonal Antibody |
| Other name | Anti-CAMK2D Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CAMK2D |
| Short name | Anti-CAMK2D (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-calcium/calmodulin-dependent protein phosphorylation catalyst II delta (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CAMK2D and IDBG-34988 and ENSG00000145349 and 817, CAMK2D and IDBG-640024 and ENSBTAG00000014463 and 532713, CAMKD, Camk2d and IDBG-192589 and ENSMUSG00000053819 and 108058, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0001666 and response to hypoxia and biological process this GO :0002026 and regulation of the force of heart contraction and biological process this GO :0003254 and regulation of membrane depolarization and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004683 and calmodulin-dependent protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005954 and calcium- and calmodulin-dependent protein kinase complex and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007268 and synaptic transmission and biological process this GO :0008016 and regulation of heart contraction and biological process this GO :0010389 and regulation of G2/M transition of mitotic cell cycle and biological process this GO :0010613 and positive regulation of cardiac muscle hypertrophy and biological process this GO :0010881 and regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion and biological process this GO :0014911 and positive regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004683: calmodulin-dependent protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005516: calmodulin binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004683: calmodulin-dependent protein kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005516: calmodulin binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0017080: sodium channel regulator activity, this GO :0031432: titin binding, this GO :0044325: ion channel binding, this GO :0050998: nitric-oxide synthase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017080: sodium channel regulator activity and also this GO :0031432: titin binding and also this GO :0044325: ion channel binding and also this GO :0050998: nitric-oxide synthase binding, transferring phosphorus-containing groups and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030007 and cellular potassium ion homeostasis and biological process this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0031432 and titin binding and molecular function this GO :0033017 and sarcoplasmic reticulum membrane and cellular component this GO :0034704 and calcium channel complex and cellular component this GO :0035022 and positive regulation of Rac protein signal transduction and biological process this GO :0043234 and protein complex and cellular component this GO :0044325 and ion channel binding and molecular function this GO :0046777 and protein autophosphorylation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0050998 and nitric-oxide synthase binding and molecular function this GO :0055119 and relaxation of cardiac muscle and biological process this GO :0060314 and regulation of ryanodine-sensitive calcium-release channel activity and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060341 and regulation of cellular localization and biological process this GO :0061049 and cell growth involved in cardiac muscle cell development and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071277 and cellular response to calcium ion and biological process this GO :0086003 and cardiac muscle cell contraction and biological process this GO :0086091 and regulation of heart rate by cardiac conduction and biological process this GO :1901725 and regulation of histone deacetylase activity and biological process this GO :1901897 and regulation of relaxation of cardiac muscle and biological process this GO :1902305 and regulation of sodium ion transmembrane transport and biological process this GO :2000649 and regulation of sodium ion transmembrane transporter activity and biological process, calcium/calmodulin-dependent protein kinase II delta |
| Identity | 1462 |
| Gene | CAMK2D |
| Long gene name | calcium/calmodulin dependent protein kinase II delta |
| Synonyms gene | CAMKD |
| Synonyms gene name | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta |
| Locus | 4q26 |
| Discovery year | 1993-11-24 |
| GenBank acession | U50361 |
| Entrez gene record | 817 |
| Havana BLAST/BLAT | OTTHUMG00000132910 |