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Anti-CAPS1 (Polyclonal), ALEXA Fluor 594

Anti-CAPS1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCAPS1
SpecificityThis antibody reacts specifically with CAPS1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CAPS1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances, CAPS proteins help to regulate cell fate during neuronal development, CAPS-1 is thought to regulate catecholamine release from neuronal cells, Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism, The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, Through their regulation of neurotrophin release from granule cells, as well as regulation of phospholipid binding, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) from granule cells, Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CAPS1 MGC126562
Also known asCAPS1 Polyclonal Antibody
Other nameAnti-CAPS1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCAPS1
Short nameAnti-CAPS1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CAPS1 (polyclonal)
Alternative techniquepolyclonals
Identity 1487
Gene CAPS
Long gene name calcyphosine
Synonyms name calcyphosine 1 thyroid protein p24
Locus 19p13, 3
Discovery year 1990-05-31
GenBank acession X97966
Entrez gene record 828
Pubmed identfication 9224948 2265558
RefSeq identity NM_004058
Classification EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000180619

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