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Anti-CARD7 (Polyclonal), ALEXA Fluor 594

Anti-CARD7 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCARD7
SpecificityThis antibody reacts specifically with CARD7
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CARD7/NALP1
Gene ID22861
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death, Jul 2008], Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, Overexpression of this gene was demonstrated to induce apoptosis in cells, The encoded protein contains a distinct N-terminal pyrin-like motif, This protein interacts strongly with caspase 2 and weakly with caspase 9, [provided by RefSeq, but the biological validity of some variants has not been determined, which is possibly involved in protein-protein interactions, This gene encodes a member of the Ced-4 family of apoptosis proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA0926 DKFZp586O1822 CARD7 NAC CLR17, 1 DEFCAP VAMAS1
Also known asCARD7 Polyclonal Antibody
Other nameAnti-CARD7 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCARD7
Short nameAnti-CARD7 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CARD7 (polyclonal)
Alternative techniquepolyclonals
Identity 14374
Gene NLRP1
Long gene name NLR family pyrin domain containing 1
Synonyms gene NALP1 SLEV1
Synonyms gene name NACHT, leucine rich repeat and PYD (pyrin domain) containing 1 systemic lupus erythematosus, vitiligo-related 1
Synonyms name leucine rich repeat and pyrin domain containing 1 , nucleotide-binding oligomerization domain
Locus 17p13
Discovery year 2003-10-28
GenBank acession AB023143
Entrez gene record 22861
Pubmed identfication 8781126 12563287 17377159
RefSeq identity NM_033004
Classification Caspase recruitment domain containing NLR family Pyrin domain containing
Havana BLAST/BLAT OTTHUMG00000132419

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