Name : Anti-CARM1(Ser228) (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :516
SKU : GEN9994855572
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CARM1 Ser228 |
| Specificity | This antibody reacts specifically with CARM1(Ser228) |
| Modification | Phosphorylation |
| Modification site | Ser228 |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic phosphopeptide derived from human CARM1 around the phosphorylation site of Ser228 |
| Gene ID | 10498 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | During myogenic transcriptional activation, During nuclear hormone receptor activation and TCF7L2/TCF4 activation, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription, Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, acts together with NCOA3/ACTR as a coactivator for MEF2C, and mRNA stability, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling, transcription regulation, Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PRMT4 |
| Also known as | CARM1(Ser228) Polyclonal Antibody |
| Other name | Anti-CARM1(Ser228) Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CARM1(Ser228) |
| Short name | Anti-CARM1(Ser228) (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CARM1(Ser228) (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 23393 |
| Gene | CARM1 |
| Long gene name | coactivator associated arginine methyltransferase 1 |
| Locus | 19p13, 2 |
| Discovery year | 2003-11-14 |
| GenBank acession | AF055027 |
| Entrez gene record | 10498 |
| Pubmed identfication | 10381882 11724789 |
| RefSeq identity | NM_199141 |
| Classification | Protein arginine methyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000180699 |