Name : Anti-CART1/Alx1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4939929987
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CART1/Alx1 |
| Specificity | This antibody reacts specifically with CART1/Alx1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CART1/Alx1 |
| Gene ID | 8092 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | ALX1 also contains an OAR domain, ALX1 is a homeobox transcription factor that regulates downstream target genes and has specifically shown to act as a transcriptional repressor for rat prolactin in vivo, As well as having a homeobox domain, First characterized from a rat chondrosarcoma tumor cell line, Homozygous ALX1 deficient mice are born with acrania and meroanencephaly, It has also been suggested that ALX1 cooperates with ALX4 in limb development and craniofacial bone formation, suggesting ALX1 function in the development of the neural tube, which has been suggested to be important for DNA binding or protein-protein interactions and transactivation, ALX1 is a 326 amino acid protein specific to cervix and cartilage tissues |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | CART1/Alx1 Polyclonal Antibody |
| Other name | Anti-CART1/Alx1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CART1/Alx1 |
| Short name | Anti-CART1/Alx1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CART1/Alx1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 1494 |
| Gene | ALX1 |
| Long gene name | ALX homeobox 1 |
| Synonyms gene | CART1 |
| Synonyms gene name | cartilage paired-class homeoprotein 1 |
| Locus | 12q21, 31 |
| Discovery year | 1999-08-26 |
| GenBank acession | U31986 |
| Entrez gene record | 8092 |
| Pubmed identfication | 8756334 7592751 |
| RefSeq identity | NM_006982 |
| Classification | PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT | OTTHUMG00000169820 |