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Anti-CASC3(Tyr181) (Polyclonal), ALEXA Fluor 594

Anti-CASC3(Tyr181) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCASC3 Tyr181
SpecificityThis antibody reacts specifically with CASC3(Tyr181)
ModificationPhosphorylation
Modification siteTyr181
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human CASC3 around the phosphorylation site of Tyr181
Gene ID22794
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes, In mammalian cells, Its fly homolog, MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer, Magoh and Y14, The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, The function of MLN51 in mammals remains elusive, and translation, are core components of the exon junction complex (EJC), as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte, named barentsz, nonsense-mediated mRNA decay, the human homologs of mago nashi and tsunagi, this complex serves as a key modulator of spliced mRNA metabolism, &euro, &ldquo, The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonâ, exon junctions as a consequence of pre-mRNA splicing
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms MLN51 BTZ
Also known asCASC3(Tyr181) Polyclonal Antibody
Other nameAnti-CASC3(Tyr181) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCASC3(Tyr181)
Short nameAnti-CASC3(Tyr181) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CASC3(Tyr181) (polyclonal)
Alternative techniquepolyclonals
Identity 17040
Gene CASC3
Long gene name cancer susceptibility 3
Synonyms gene name cancer susceptibility candidate 3
Locus 17q21, 1
Discovery year 2004-02-11
GenBank acession X80199
Entrez gene record 22794
Pubmed identfication 7490069 18332872
RefSeq identity NM_007359
Classification Exon junction complex
Havana BLAST/BLAT OTTHUMG00000133323

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