Filters

Anti-Caspase-10 (Polyclonal), ALEXA Fluor 594

Anti-Caspase-10 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCaspase-10
SpecificityThis antibody reacts specifically with Caspase-10
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human Caspase-10
Gene ID843
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information 10b, 10c, 4, 6, 7, 8, 8, Caspase 10 (Mch4, Caspase 10 can cleave and activate caspases 3, Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody, Four isoforms of caspase 10 (caspase 10a, ICE-LAP4, Interestingly, It is a large prodomain caspase classified together with caspases 2, The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein, The mature form of caspase 10 comprises two subunits, This is followed by cleavage of numerous key proteins, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested, and 10d) having the same prodomain but different mature large and small subdomain, and 9, and 9 as a signaling caspase, have been described, including the nuclear protein PARP, p23/p17 (splice isoforms) and p12, Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms ALPS2, Apoptosis related cysteine peptidase, Apoptotic protease Mch 4, CASP 10, CASP10, CASP10 protein, Caspase 10 apoptosis related cysteine peptidase, Caspase 10 apoptosis related cysteine protease, Caspase10, FADD Like Ice 2, FAS associated death domain protein interleukin 1B converting enzyme 2, FLICE 2, FLICE2, Fas Associated Death Domain Protein, ICE Like Apoptotic Protease 4, Interleukin 1B Converting Enzyme 2, MCH 4, MCH4, ALPS 2
Also known asCaspase-10 Polyclonal Antibody
Other nameAnti-Caspase-10 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCaspase-10
Short nameAnti-Caspase-10 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-caspase-10 (polyclonal)
Alternative techniquepolyclonals

Subscribe to our Newsletter