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Anti-Caspase 3 (Polyclonal), ALEXA Fluor 594

Anti-Caspase 3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCaspase-3
SpecificityThis antibody reacts specifically with Caspase 3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Caspase 3(Active)
Gene ID836
Swiss ProtP42574
Applications IF(ICC), IF(IHC-P), FCM
Applications with corresponding dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Bovine, Goat, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information -7 and -9, At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond, Cleaves and activates caspase-6, Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain, Involved in the cleavage of huntingtin, Triggers cell adhesion in sympathetic neurons through RET cleavage, Involved in the activation cascade of caspases responsible for apoptosis execution
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asCaspase 3 Polyclonal Antibody
Other nameAnti-Caspase 3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCaspase 3
Short nameAnti-Caspase 3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-caspase 3 (polyclonal)
Alternative techniquepolyclonals
Identity 43777
Gene CASP1P3
Long gene name caspase 1 pseudogene 3
Synonyms gene name apoptosis-related cysteine peptidase pseudogene 3 , caspase 1
Locus 11q22, 3
Discovery year 2012-02-24
Entrez gene record 100422634
RefSeq identity NG_024409

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