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Anti-CASPASE-8 (C-TERMINAL)

Anti-CASPASE-8 (C-TERMINAL) size: 100ug 514

Supplier MBS POLYCLONALS 1
Price 514
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-RABBIT ANTI CASPASE-8 (C-TERMINAL)
Alternative name2RABBIT ANTI CASPASE-8 (C-TERMINAL)
Alternative name3Lapin ANTI CASPASE-8 (C-TERMINAL)
Alternative name4CASPASE-8
Alternative name5N/A
Other names Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8, FADD-homologous ICE/CED-3-like protease, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE-like apoptotic protease 5, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein, MORT1-associated ced-3 homolog, MORT1-associated ced-3 homolog, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, apoptotic cysteine protease, apoptotic protease Mch-5, caspase 8, caspase 8, caspase-8, caspase-8 isoform C
Gene nameN/A
Gene name synonimsN/A
Other gene names ALPS2B, CAP4, CASP-8, CASP8, Casp-8, FLICE, FLICE, MACH, MACH, MCH5, MCH5, CASP8
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismRabbit
Species reactivityHuman
Specificity and cross-reactivity Active Caspase-8 is capable of cleaving all other known caspases, Caspase-8 is classified as an initiator caspase and acts as the most upstream trigger of Fas-Receptor (CD95) and tumour necrosis factor receptor 1 (TNFR1) mediated apoptosis, FADD in turn then binds via death effector domains (DEDs) to procaspase-8, Upon activation, along with the Bcl-2 associated protein p28Bap31, and also cleaves the Bcl-2 family member BH3-interacting domain death agonist (BID), links with the adaptor molecule FADD via corresponding death domains (DD), otherwise known as Fas-linked ICE-like protease (FLICE), the cell death receptor Fas, which shares homology with both Fas-associated via death domain (FADD) and the ICE/Ced-3 family of cysteine proteases, which then undergoes oligomerization and autocatalytic activation, CASPASE-8 This item recognises an epitope within the c-terminal region (CT) of caspase-8
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
Concentration0 mg/ml, IgG concentration 1
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for:Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Gene targetCASPASE-8
Short nameAnti-CASPASE-8 (C-TERMINAL)
Alternative nameantibody to-caspase-8 (C-TERMINAL)

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