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Anti-caspase-9 p10 (Polyclonal), ALEXA Fluor 594

Anti-caspase-9 p10 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/Peptidecaspase-9 p10
SpecificityThis antibody reacts specifically with caspase-9 p10
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Mitochondrion, Nucleus
Antigen SourceKLH conjugated synthetic peptide derived from human caspase-9 subunit p10
Gene ID842
Swiss ProtP55211
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3, Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9, Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, Proteolytically cleaves poly(ADP-ribose) polymerase (PARP), Involved in the activation cascade of caspases responsible for apoptosis execution
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, Caspase-9, ICE-LAP6, ICE-like apoptotic protease 6, PPP1R56, MCH6
Also known ascaspase-9 p10 Polyclonal Antibody
Other nameAnti-caspase-9 p10 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Description CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways, Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetcaspase-9 p10
Short nameAnti-caspase-9 p10 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-caspase-9 p10 (polyclonal)
Alternative techniquepolyclonals

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