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Anti-Cathepsin C/DPP1 (Polyclonal), ALEXA Fluor 594

Anti-Cathepsin C/DPP1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCathepsin C/DPP1
SpecificityThis antibody reacts specifically with Cathepsin C/DPP1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human DPP-I
Gene ID1075
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, It is composed of a dimer of disulfide-linked heavy and light chains, Multiple transcript variants encoding different isoforms have been found for this gene, This enzyme requires chloride ions for activity and can degrade glucagon, [provided by RefSeq], a member of the peptidase C1 family, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme, both produced from a single protein precursor, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells, The protein encoded by this gene
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DPP1
Also known asCathepsin C/DPP1 Polyclonal Antibody
Other nameAnti-Cathepsin C/DPP1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene CTSC
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCathepsin C/DPP1
Short nameAnti-Cathepsin C/DPP1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Cathepsin C/DPP1 (polyclonal)
Alternative techniquepolyclonals
Identity 2528
Long gene name cathepsin C
Synonyms gene PLS PALS
Synonyms name dipeptidyl peptidase 1
Locus 11q14, 2
Discovery year 1995-11-08
GenBank acession AK223038
Entrez gene record 1075
Pubmed identfication 7649281 9092576
RefSeq identity NM_001814
Classification Cathepsins
Havana BLAST/BLAT OTTHUMG00000167290
Locus Specific Databases CTSCbase: Mutation registry for Papillon-Lefevre syndrome LRG_50

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