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Anti-Cathepsin D/CTSD (Polyclonal), ALEXA Fluor 594

Anti-Cathepsin D/CTSD (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCathepsin D/CTSD
SpecificityThis antibody reacts specifically with Cathepsin D/CTSD
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Lysosome, Secreted
Antigen SourceKLH conjugated synthetic peptide derived from human Capsin D
Gene ID1509
Swiss ProtP07339
Applications IF(ICC), IF(IHC-P)
Applications with corresponding dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease, Acid protease active in intracellular protein breakdown
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CLN10
Also known asCathepsin D/CTSD Polyclonal Antibody
Other nameAnti-Cathepsin D/CTSD Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene CTSD
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCathepsin D/CTSD
Short nameAnti-Cathepsin D/CTSD (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Cathepsin D/cathepsin D (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target CATD and IDBG-645332 and ENSBTAG00000007622 and 282883, CLN10 and CPSD and HEL-S-130P, CTSD and IDBG-19613 and ENSG00000117984 and 1509, Ctsd and IDBG-212523 and ENSMUSG00000007891 and 13033, Extracellular, protein binding, this GO :0004190 and aspartic-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005764 and lysosome and cellular component this GO :0006508 and proteolysis and biological process this GO :0008219 and cell death and biological process this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042470 and melanosome and cellular component this GO :0043202 and lysosomal lumen and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004190: aspartic-type endopeptidase activity, this GO :0004190: aspartic-type endopeptidase activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, cathepsin D
Identity 2529
Long gene name cathepsin D
Synonyms gene CPSD
Synonyms gene name cathepsin D (lysosomal aspartyl protease)
Synonyms name ceroid-lipofuscinosis, neuronal 10
Locus 11p15, 5
Discovery year 1986-01-01
GenBank acession M11233
Entrez gene record 1509
Pubmed identfication 3927292
RefSeq identity NM_001909
Classification Cathepsins
Havana BLAST/BLAT OTTHUMG00000044760
Locus Specific Databases NCL Mutations , Neuronal Ceroid Lipofuscinoses

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