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Anti-Caveolin-2 (Polyclonal), ALEXA Fluor 594

Anti-Caveolin-2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCaveolin-2
SpecificityThis antibody reacts specifically with Caveolin-2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Caveolin-2
Gene ID858
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation, CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane, Cell membrane, Cytoplasm, Golgi apparatus membrane, Interacts directly with G-protein alpha subunits and can functionally regulate their activity, Membrane >, Membrane protein of caveolae, Positive regulator of cellular mitogenesis of the MAPK signaling pathway, Potential hairpin-like structure in the membrane, Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, Ser-36-phosphorylated form resides in intracellular compartments, The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells, Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity), Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane, and the subsequent regulation of cell cycle progression, caveola, skeletal myoblasts and fibroblasts, smooth muscle cells, Cellular localization: Nucleus, May act as a scaffolding protein within caveolar membranes, Tissue specificity: Expressed in endothelial cells
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CAV2, CAV2_HUMAN, Caveolae protein 20 kD, Caveolin 2, Caveolin 2 isoform a and b, Caveolin 2 isoform c, Caveolin-2, Caveolin2, MGC12294, CAV
Also known asCaveolin-2 Polyclonal Antibody
Other nameAnti-Caveolin-2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCaveolin-2
Short nameAnti-Caveolin-2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Caveolin-2 (polyclonal)
Alternative techniquepolyclonals

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