Name : Anti-Caveolin-2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN4385240917
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | Caveolin-2 |
| Specificity | This antibody reacts specifically with Caveolin-2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human Caveolin-2 |
| Gene ID | 858 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation, CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane, Cell membrane, Cytoplasm, Golgi apparatus membrane, Interacts directly with G-protein alpha subunits and can functionally regulate their activity, Membrane >, Membrane protein of caveolae, Positive regulator of cellular mitogenesis of the MAPK signaling pathway, Potential hairpin-like structure in the membrane, Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, Ser-36-phosphorylated form resides in intracellular compartments, The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells, Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity), Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane, and the subsequent regulation of cell cycle progression, caveola, skeletal myoblasts and fibroblasts, smooth muscle cells, Cellular localization: Nucleus, May act as a scaffolding protein within caveolar membranes, Tissue specificity: Expressed in endothelial cells |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CAV2, CAV2_HUMAN, Caveolae protein 20 kD, Caveolin 2, Caveolin 2 isoform a and b, Caveolin 2 isoform c, Caveolin-2, Caveolin2, MGC12294, CAV |
| Also known as | Caveolin-2 Polyclonal Antibody |
| Other name | Anti-Caveolin-2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | Caveolin-2 |
| Short name | Anti-Caveolin-2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-Caveolin-2 (polyclonal) |
| Alternative technique | polyclonals |