Name : Anti-CCDC39 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5858044856
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CCDC39 |
| Specificity | This antibody reacts specifically with CCDC39 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CCDC39 |
| Gene ID | 339829 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | A disorder characterized by abnormalities of motile cilia, Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, Not required for outer dynein arm complexes assembly, Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome, Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, due to dysfunction of monocilia at the embryonic node, in lungs and testis, reduced fertility is often observed in male patients due to abnormalities of sperm tails, thereby playing a central role in motility in cilia and flagella, to a lesser extent, which are responsible for ciliary beat regulation, Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) , Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, Tissue specificity:Mainly expressed in nasal brushings and |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | DKFZp434A128 CILD14 FAP59 |
| Also known as | CCDC39 Polyclonal Antibody |
| Other name | Anti-CCDC39 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CCDC39 |
| Short name | Anti-CCDC39 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CCDC39 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 25244 |
| Gene | CCDC39 |
| Long gene name | coiled-coil domain containing 39 |
| Locus | 3q26, 33 |
| Discovery year | 2005-11-11 |
| GenBank acession | BC047103 |
| Entrez gene record | 339829 |
| Pubmed identfication | 21131972 |
| RefSeq identity | XM_291028 |
| Havana BLAST/BLAT | OTTHUMG00000157857 |