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Anti-CCKAR (Polyclonal), ALEXA Fluor 594

Anti-CCKAR (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCCKAR
SpecificityThis antibody reacts specifically with CCKAR
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human CCKAR
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A (CCKAR)and B (CCKBR), CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion, Class A receptors have also been described in the anterior pituitary, Further, It appears to play a role in slowing gastric emptying, Parkinson disease, These appear to be mediated through 2 general classes of receptors, Through binding to class A receptors, and drug addiction, and potentiation of insulin secretion, and regions of the central nervous system, based on their binding affinities for CCK/gastrin family peptides, it has been implicated as a mediator of pancreatic growth and tumorigenesis, myenteric plexus, relaxation of the sphincter of Oddi, schizophrenia, where they have been implicated in the pathogenesis of feeding disorders, The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asCCKAR Polyclonal Antibody
Other nameAnti-CCKAR Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCCKAR
Short nameAnti-CCKAR (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-cholecystokinin A receptor (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target CCK-A and CCK1-R and CCK1R and CCKRA, CCKAR and IDBG-12723 and ENSG00000163394 and 886, CCKAR and IDBG-641476 and ENSBTAG00000004988 and 506207, Cckar and IDBG-164710 and ENSMUSG00000029193 and 12425, Plasma membranes, cholecystokinin receptor activity, this GO :0001764 and neuron migration and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004951 and cholecystokinin receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007409 and axonogenesis and biological process this GO :0007584 and response to nutrient and biological process this GO :0007586 and digestion and biological process this GO :0007631 and feeding behavior and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030900 and forebrain development and biological process this GO :0038188 and cholecystokinin signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004951: cholecystokinin receptor activity, this GO :0004951: cholecystokinin receptor activity, cholecystokinin A receptor
Identity 1570
Gene CCKAR
Long gene name cholecystokinin A receptor
Locus 4p15, 2
Discovery year 1993-07-13
GenBank acession L19315
Entrez gene record 886
Classification Cholecystokinin receptors
Havana BLAST/BLAT OTTHUMG00000128567

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