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Anti-CCR4 (Polyclonal), ALEXA Fluor 594

Anti-CCR4 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCCR4
SpecificityThis antibody reacts specifically with CCR4
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human CCR-4
Gene ID1233
Swiss ProtP51679
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates, In the CNS, The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system, could mediate hippocampal-neuron survival, High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CCR4 KIAA1194 Ccr4a
Also known asCCR4 Polyclonal Antibody
Other nameAnti-CCR4 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCCR4
Short nameAnti-CCR4 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-chemokine (C-C motif) receptor 4 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target C-C chemokine receptor activity, CC-CKR-4 and CD194 and ChemR13 and CKR4 and CMKBR4 and HGCN:14099 and K5-5, CCR4 and IDBG-23908 and ENSG00000183813 and 1233, CCR4 and IDBG-644121 and ENSBTAG00000034883 and 100851774, Ccr4 and IDBG-203512 and ENSMUSG00000047898 and 12773, Cell surfaces, this GO :0001764 and neuron migration and biological process this GO :0002507 and tolerance induction and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0009314 and response to radiation and biological process this GO :0009617 and response to bacterium and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0045087 and innate immune response and biological process this GO :0046677 and response to antibiotic and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0016493: C-C chemokine receptor activity, this GO :0004950: chemokine receptor activity, this GO :0016493: C-C chemokine receptor activity, 408019, chemokine (C-C motif) receptor 4
Identity 14099
Gene CNOT6
Long gene name CCR4-NOT transcription complex subunit 6
Synonyms gene name CCR4-NOT transcription complex, subunit 6
Locus 5q35, 3
Discovery year 2001-03-30
GenBank acession AB033020
Entrez gene record 57472
Pubmed identfication 11889047
RefSeq identity NM_015455
Classification CCR4-NOT transcription complex
Havana BLAST/BLAT OTTHUMG00000130935

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