Name : Anti-CD109 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2893164043
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CD109 |
| Specificity | This antibody reacts specifically with CD109 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Cell membrane |
| Antigen Source | KLH conjugated synthetic peptide derived from human CD109 |
| Gene ID | 135228 |
| Swiss Prot | Q6YHK3 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Although it has been suggested that T-cell CD109 may play a role in antibody-inducing T-helper function and it is known that platelet CD109 carries the Gov alloantigen system, It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170 kd found onendothelial cells, activated platelets and T-cells and on a subset of hematopoietic stem and progenitor cells, the role of CD109 in hematopoietic cells remains largely unknown, CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes and upregulation of CD109 expression has been observed in several different types of tumour, CD109 is a a novel member of the alpha2-macroglobulin (alpha2M)/complement superfamily |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ38569 DKFZp762L1111 CPAMD7 |
| Also known as | CD109 Polyclonal Antibody |
| Other name | Anti-CD109 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CD109 |
| Short name | Anti-CD109 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CD109 molecule (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CD109 and IDBG-629598 and ENSBTAG00000013222 and 534043, CD109 and IDBG-92570 and ENSG00000156535 and 135228, Cd109 and IDBG-187096 and ENSMUSG00000046186 and 235505, Extracellular, this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0061045 and negative regulation of wound healing and biological process, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0004867: serine-type endopeptidase inhibitor activity and also this GO :0050431: transforming growth factor beta binding, this GO :0004867: serine-type endopeptidase inhibitor activity, this GO :0050431: transforming growth factor beta binding, transforming growth factor beta binding, CD109 molecule |
| Identity | 21685 |
| Gene | CD109 |
| Long gene name | CD109 molecule |
| Synonyms gene name | CD109 antigen (Gov platelet alloantigens) |
| Locus | 6q13 |
| Discovery year | 2003-07-04 |
| GenBank acession | AF410459 |
| Entrez gene record | 135228 |
| Pubmed identfication | 11861284 11861285 |
| RefSeq identity | NM_133493 |
| Classification | CD molecules C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000015040 |
| Locus Specific Databases | LRG_1002 |