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Anti-CD109 (Polyclonal), ALEXA Fluor 594

Anti-CD109 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCD109
SpecificityThis antibody reacts specifically with CD109
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCell membrane
Antigen SourceKLH conjugated synthetic peptide derived from human CD109
Gene ID135228
Swiss ProtQ6YHK3
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Although it has been suggested that T-cell CD109 may play a role in antibody-inducing T-helper function and it is known that platelet CD109 carries the Gov alloantigen system, It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170 kd found onendothelial cells, activated platelets and T-cells and on a subset of hematopoietic stem and progenitor cells, the role of CD109 in hematopoietic cells remains largely unknown, CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes and upregulation of CD109 expression has been observed in several different types of tumour, CD109 is a a novel member of the alpha2-macroglobulin (alpha2M)/complement superfamily
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ38569 DKFZp762L1111 CPAMD7
Also known asCD109 Polyclonal Antibody
Other nameAnti-CD109 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCD109
Short nameAnti-CD109 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CD109 molecule (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target CD109 and IDBG-629598 and ENSBTAG00000013222 and 534043, CD109 and IDBG-92570 and ENSG00000156535 and 135228, Cd109 and IDBG-187096 and ENSMUSG00000046186 and 235505, Extracellular, this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0061045 and negative regulation of wound healing and biological process, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0004867: serine-type endopeptidase inhibitor activity and also this GO :0050431: transforming growth factor beta binding, this GO :0004867: serine-type endopeptidase inhibitor activity, this GO :0050431: transforming growth factor beta binding, transforming growth factor beta binding, CD109 molecule
Identity 21685
Gene CD109
Long gene name CD109 molecule
Synonyms gene name CD109 antigen (Gov platelet alloantigens)
Locus 6q13
Discovery year 2003-07-04
GenBank acession AF410459
Entrez gene record 135228
Pubmed identfication 11861284 11861285
RefSeq identity NM_133493
Classification CD molecules C3 and PZP like, alpha-2-macroglobulin domain containing
Havana BLAST/BLAT OTTHUMG00000015040
Locus Specific Databases LRG_1002

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