Name : Anti-CD14 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5803539788
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CD14 |
| Specificity | This antibody reacts specifically with CD14 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from mouse CD14 |
| Gene ID | 12475 |
| Swiss Prot | P10810 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts via MyD88, TIRAP and TRAF6, Up-regulates cell surface molecules, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, cytokine secretion and the inflammatory response, including adhesion molecules (By similarity), leading to NF-kappa-B activation, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS), In concert with LBP |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | CD14 Polyclonal Antibody |
| Other name | Anti-CD14 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CD14 |
| Short name | Anti-CD14 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CD14 molecule (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | CD14 and IDBG-49157 and ENSG00000170458 and 929, CD14 and IDBG-646064 and ENSBTAG00000015032 and 281048, Cd14 and IDBG-138525 and ENSMUSG00000051439 and 12475, Extracellular, lipoteichoic acid binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0001847 and opsonin receptor activity and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0009408 and response to heat and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016019 and peptidoglycan receptor activity and molecular function this GO :0031225 and anchored component of membrane and cellular component this GO :0032026 and response to magnesium ion and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045471 and response to ethanol and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070891 and lipoteichoic acid binding and molecular function this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process, this GO :0001530: lipopolysaccharide binding, this GO :0001530: lipopolysaccharide binding and also this GO :0001847: opsonin receptor activity and also this GO :0005515: protein binding and also this GO :0016019: peptidoglycan receptor activity and also this GO :0070891: lipoteichoic acid binding, this GO :0001847: opsonin receptor activity, this GO :0005515: protein binding, this GO :0016019: peptidoglycan receptor activity, this GO :0070891: lipoteichoic acid binding, CD14 molecule |
| Identity | 1628 |
| Gene | CD14 |
| Long gene name | CD14 molecule |
| Synonyms gene name | CD14 antigen |
| Locus | 5q31, 3 |
| Discovery year | 1988-05-31 |
| Entrez gene record | 929 |
| Pubmed identfication | 2472171 2462937 |
| RefSeq identity | NM_000591 |
| Classification | CD molecules Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000129507 |