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Anti-CD18 (Polyclonal), ALEXA Fluor 594

Anti-CD18 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCD18
SpecificityThis antibody reacts specifically with CD18
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human Integrin beta 2
Gene ID3689
Swiss ProtP05107
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ICAM2, ICAM3 and ICAM4, Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1, Integrin alpha-M/beta-2 is also a receptor for factor X, Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain, Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain, Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen, Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation, Integrin alpha-L/beta-2 is a receptor for ICAM1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LFA-1 MAC-1
Also known asCD18 Polyclonal Antibody
Other nameAnti-CD18 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCD18
Short nameAnti-CD18 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CD18 (polyclonal)
Alternative techniquepolyclonals
Identity 6155
Gene ITGB2
Long gene name integrin subunit beta 2
Synonyms gene CD18 MFI7
Synonyms gene name beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin
Synonyms name complement component 3 receptor 3 and 4 subunit
Locus 21q22, 3
Discovery year 1986-01-01
GenBank acession AK222505
Entrez gene record 3689
RefSeq identity NM_000211
Classification Complement system Integrin beta subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000090257
Locus Specific Databases ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76

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