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Anti-CD18 (Ser756 + Thr758 + Thr759), ALEXA Fluor 594

Anti-CD18 (Ser756 + Thr758 + Thr759), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCD18 Ser756 + Thr758 + Thr759
SpecificityThis antibody reacts specifically with CD18 (Ser756 + Thr758 + Thr759)
ModificationPhosphorylation
Modification siteSer756 + Thr758 + Thr759
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsCytoplasm
Antigen Source Thr758/759, KLH conjugated synthetic phosphopeptide derived from human CD18 around the phosphorylation site of Ser756
Gene ID3689
Swiss ProtP05107
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ICAM2, ICAM3 and ICAM4, Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1, Integrin alpha-M/beta-2 is also a receptor for factor X, Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain, Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain, Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen, Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation, Integrin alpha-L/beta-2 is a receptor for ICAM1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms LFA-1 MAC-1
Also known asCD18 (Ser756 + Thr758 + Thr759) Antibody
Other nameAnti-CD18 (Ser756 + Thr758 + Thr759)
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetCD18 (Ser756 + Thr758 + Thr759)
Short nameAnti-CD18 (Ser756 + Thr758 + Thr759) Fluor 594
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CD18 (Ser756 and Thr758 and Thr759)
Identity 6155
Gene ITGB2
Long gene name integrin subunit beta 2
Synonyms gene CD18 MFI7
Synonyms gene name beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin
Synonyms name complement component 3 receptor 3 and 4 subunit
Locus 21q22, 3
Discovery year 1986-01-01
GenBank acession AK222505
Entrez gene record 3689
RefSeq identity NM_000211
Classification Complement system Integrin beta subunits CD molecules
Havana BLAST/BLAT OTTHUMG00000090257
Locus Specific Databases ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76

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