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Anti-CD59 (Polyclonal), ALEXA Fluor 594

Anti-CD59 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCD59
SpecificityThis antibody reacts specifically with CD59
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsHelical
Antigen SourceKLH conjugated synthetic peptide derived from human CD59
Gene ID966
Swiss ProtP13987
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Acts by binding to the C8 and/or C9 complements of the assembling MAC, Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase, The soluble form from urine retains its specific complement binding activity, This inhibitor appears to be species-specific, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore, Potent inhibitor of the complement membrane attack complex (MAC) action
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms 16, 3A5 EJ16 EJ30 EL32 G344 p18-20
Also known asCD59 Polyclonal Antibody
Other nameAnti-CD59 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCD59
Short nameAnti-CD59 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, complement regulatory protein (polyclonal), antibody to-CD59 molecule
Alternative techniquepolyclonals
Alternative to gene target 16, CD59 and IDBG-38813 and ENSG00000085063 and 966, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574, Extracellular, complement regulatory protein, protein binding, this GO :0001775 and cell activation and biological process this GO :0001848 and complement binding and molecular function this GO :0001971 and negative regulation of activation of membrane attack complex and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0030449 and regulation of complement activation and biological process this GO :0031362 and anchored component of external side of plasma membrane and cellular component this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043218 and compact myelin and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001848: complement binding, this GO :0001848: complement binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, 3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 molecule
Identity 1689
Gene CD59
Long gene name CD59 molecule
Synonyms gene MIC11 MIN1 MSK21 MIN2 MIN3
Synonyms gene name CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16, EJ16, EJ30, EL32 and G344) CD59 antigen, complement regulatory protein , complement regulatory protein CD59 molecule, 3A5
Locus 11p13
Discovery year 1989-06-30
Entrez gene record 966
Pubmed identfication 7691713
RefSeq identity NM_203329
Classification Complement system CD molecules LY6/PLAUR domain containing
Havana BLAST/BLAT OTTHUMG00000166270
Locus Specific Databases CD59base: Mutation registry for CD59 deficiency LRG_41

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