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Anti-CD95 (Polyclonal), ALEXA Fluor 594

Anti-CD95 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCD95
SpecificityThis antibody reacts specifically with CD95
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from mouse FAS
Gene ID14102
Swiss ProtP25446
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Rat (Rattus norvegicus), Mouse (Mus musculus)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, in the antigen-stimulated suicide of mature T-cells, or both (By similarity), Receptor for TNFSF6/FASLG
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms CD95 APO-1
Also known asCD95 Polyclonal Antibody
Other nameAnti-CD95 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCD95
Short nameAnti-CD95 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CD95 (polyclonal)
Alternative techniquepolyclonals
Identity 11920
Gene FAS
Long gene name Fas cell surface death receptor
Synonyms gene FAS1 APT1 TNFRSF6
Synonyms gene name member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily
Synonyms name TNF receptor superfamily member 6
Locus 10q23, 31
Discovery year 1992-06-25
GenBank acession M67454
Entrez gene record 355
Pubmed identfication 1385299 1385309
Classification CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000018701
Locus Specific Databases Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134

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