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Anti-Cdc14A (Polyclonal), ALEXA Fluor 594

Anti-Cdc14A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCdc14A
SpecificityThis antibody reacts specifically with Cdc14A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Cdc14A
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Cdc14a dephosphorylates hCdh1 and activates APCCdh1, Cdc14a phosphatase plays a role in the regulation of the centrosome cycle, Deregulated human Cdc14a phosphatase disrupts centrosome separation and chromosome segregation, Human Cdc14a phosphatase is highly similar to Saccharomyces cerevisiae Cdc14 and is a member of the dual specificity protein Tyrosine phosphatase family, In addition, It interacts with and dephosphorylates tumor suppressor protein p53 and may regulate the function of p53, mitosis and cytokinesis, the Cdc14a phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release during mitosis, thereby influencing chromosome partitioning and genomic stability in human cells, In budding yeast
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms Cdc14A1 Cdc14A2 cdc14 DFNB105
Also known asCdc14A Polyclonal Antibody
Other nameAnti-Cdc14A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCdc14A
Short nameAnti-Cdc14A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Cdc14A (polyclonal)
Alternative techniquepolyclonals
Identity 1718
Gene CDC14A
Long gene name cell division cycle 14A
Synonyms gene name CDC10 (cell division cycle 10, S, cerevisiae, cerevisiae) , homolog) CDC14 cell division cycle 14 homolog A (S
Locus 1p21, 2
Discovery year 1998-12-18
GenBank acession AF000367
Entrez gene record 8556
Pubmed identfication 9367992 10409437 27259055
RefSeq identity NM_033312
Classification CDC14 phosphatases
Havana BLAST/BLAT OTTHUMG00000010987

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