Name : Anti-CDK14 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3820388418
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CDK14 |
| Specificity | This antibody reacts specifically with CDK14 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CDK14/PFTK1 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3, May also play a role in meiosis, Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo, leading to the activation of the Wnt signaling pathway, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport, whose activity is controlled by an associated cyclin, Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | PFTAIRE1 |
| Also known as | CDK14 Polyclonal Antibody |
| Other name | Anti-CDK14 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CDK14 |
| Short name | Anti-CDK14 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CDK14 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 8883 |
| Gene | CDK14 |
| Long gene name | cyclin dependent kinase 14 |
| Synonyms gene | PFTK1 |
| Synonyms gene name | PFTAIRE protein kinase 1 |
| Locus | 7q21, 13 |
| Discovery year | 1996-07-26 |
| Entrez gene record | 5218 |
| Pubmed identfication | 9202329 11313143 19884882 |
| RefSeq identity | NM_012395 |
| Classification | Cyclin dependent kinases |
| Havana BLAST/BLAT | OTTHUMG00000023649 |