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Anti-CDK5RAP2 (Polyclonal), ALEXA Fluor 594

Anti-CDK5RAP2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCDK5RAP2
SpecificityThis antibody reacts specifically with CDK5RAP2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CDK5RAP2
Gene ID55755
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity, CDK5RAP2, CDK5RAP2 associates with centrosomes throughout the cell cycle, Expressed in placenta, Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events, also known as Centrosome-associated protein 215, brain and kidney, brain weight and significant neurological deficits, heart, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1, liver, lung, pancreas, skeletal muscle, which is characterized by markedly reduced head size, Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms C48 FLJ10867 CEP215
Also known asCDK5RAP2 Polyclonal Antibody
Other nameAnti-CDK5RAP2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCDK5RAP2
Short nameAnti-CDK5RAP2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CDK5RAP2 (polyclonal)
Alternative techniquepolyclonals
Identity 18672
Gene CDK5RAP2
Long gene name CDK5 regulatory subunit associated protein 2
Synonyms gene MCPH3
Synonyms gene name microcephaly, primary autosomal recessive 3
Synonyms name centrosomin
Locus 9q33, 2
Discovery year 2002-07-22
GenBank acession BK005504
Entrez gene record 55755
Pubmed identfication 10721722 17764569 24466316
RefSeq identity NM_018249
Havana BLAST/BLAT OTTHUMG00000021043

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