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Anti-CDK8 (Polyclonal), ALEXA Fluor 594

Anti-CDK8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCDK8
SpecificityThis antibody reacts specifically with CDK8
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CDK8
Gene ID1024
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, Jul 2008], This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), [provided by RefSeq, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression, thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II, The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms K35
Also known asCDK8 Polyclonal Antibody
Other nameAnti-CDK8 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCDK8
Short nameAnti-CDK8 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CDK8 (polyclonal)
Alternative techniquepolyclonals
Identity 1779
Gene CDK8
Long gene name cyclin dependent kinase 8
Synonyms gene name cyclin-dependent kinase 8
Locus 13q12, 13
Discovery year 1998-04-29
GenBank acession X85753
Entrez gene record 1024
Pubmed identfication 7568034
Classification Cyclin dependent kinases Mediator complex
Havana BLAST/BLAT OTTHUMG00000016617

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