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Anti-CDKL5 (Polyclonal), ALEXA Fluor 594

Anti-CDKL5 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCDKL5
SpecificityThis antibody reacts specifically with CDKL5
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CDKL5
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Another family of proteins, CDKL5 (cyclin-dependent kinase-like 5) is a 1030 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family, CDKL5 is thought to play a role in cell cycle regulation, Cdk inhibitors, Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression, Defects in CDKL5 are a cause of several disorders, Expressed in brain, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity, kidney, lung, ovary, pancreas and testis, placenta, prostate, such as X-linked infantile spasm syndrome and Rett syndrome, Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin-dependent kinases (Cdks)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms EIEE2 CFAP247
Also known asCDKL5 Polyclonal Antibody
Other nameAnti-CDKL5 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCDKL5
Short nameAnti-CDKL5 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CDKL5 (polyclonal)
Alternative techniquepolyclonals
Identity 11411
Gene CDKL5
Long gene name cyclin dependent kinase like 5
Synonyms gene STK9
Synonyms gene name serine/threonine kinase 9 cyclin-dependent kinase-like 5
Locus Xp22, 13
Discovery year 1997-10-27
GenBank acession Y15057
Entrez gene record 6792
Pubmed identfication 9721213 16935860
RefSeq identity NM_003159
Classification Cyclin dependent kinases
Havana BLAST/BLAT OTTHUMG00000021214
Locus Specific Databases Mental Retardation database

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