Name : Anti-CDKN2D (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3205705877
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CDKN2D |
| Specificity | This antibody reacts specifically with CDKN2D |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human CDKN2D/p19 INK4d |
| Gene ID | 1032 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Jul 2008], The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase, The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, This protein has been shown to form a stable complex with CDK4 or CDK6, Two alternatively spliced variants of this gene, [provided by RefSeq, and prevent the activation of the CDK kinases, as well as spermatogenesis, have been reported, thus function as a cell growth regulator that controls cell cycle G1 progression, which encode an identical protein, The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | INK4D p19 |
| Also known as | CDKN2D Polyclonal Antibody |
| Other name | Anti-CDKN2D Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CDKN2D |
| Short name | Anti-CDKN2D (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, inhibits cyclin-dependent kinase 4) (polyclonal), antibody to-cyclin-dependent kinase inhibitor 2D (p19 |
| Alternative technique | polyclonals |
| Alternative to gene target | CDKN2D and IDBG-27803 and ENSG00000129355 and 1032, CDKN2D and IDBG-643316 and ENSBTAG00000010731 and 510244, Cdkn2d and IDBG-738755 and ENSMUSG00000096472 and 12581, INK4D and p19 and p19-INK4D, inhibits CDK4), nuclei, protein kinase binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000731 and DNA synthesis involved in DNA repair and biological process this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007050 and cell cycle arrest and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009411 and response to UV and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0033280 and response to vitamin D and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0048102 and autophagic cell death and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :1902230 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and biological process, this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0019901: protein kinase binding, cyclin-dependent kinase inhibitor 2D (p19 |
| Identity | 1790 |
| Gene | CDKN2D |
| Long gene name | cyclin dependent kinase inhibitor 2D |
| Synonyms gene name | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| Locus | 19p13, 2 |
| Discovery year | 1995-07-06 |
| Entrez gene record | 1032 |
| Pubmed identfication | 8575754 |
| RefSeq identity | NM_079421 |
| Classification | Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000180583 |