Filters

Anti-CDX1 (Polyclonal), ALEXA Fluor 594

Anti-CDX1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCDX1
SpecificityThis antibody reacts specifically with CDX1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CDX1
Gene ID1044
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A decrease in human Cdx1 and/or Cdx2 expression is associated with colorectal tumorigenesis, Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, Cdx1 and Cdx2 are expressed in the small intestine and colon of fetus and adult, Cdx1 positively regulates its own expression, Cdx2, Expression of the Cdx1 homeobox gene in epithelial intestinal cells promotes cellular growth and differentiation, The human Cdx1 gene maps to chromosome 5q31-q33 and encodes a 265-amino acid protein, The intestine-specific transcription factors Cdx1 and Cdx2 are candidate genes for directing intestinal development, The relative expression of Cdx1 to Cdx2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis, and Cdx4) are members of the caudal-type homeobox family of genes, differentiation, gene required for anterior-posterior regional identity, proliferation and maintenance of the intestinal phenotype, suggesting that the two genes control the normal phenotype by independent pathways, to increase sensitivity to apoptosis and to reduce cell migration, which are homologues of the Drosophila â, &euro, &euro, &tilde, &trade, The members of the murine Cdx family (Cdx1, caudalâ
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asCDX1 Polyclonal Antibody
Other nameAnti-CDX1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCDX1
Short nameAnti-CDX1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CDX1 (polyclonal)
Alternative techniquepolyclonals
Identity 1805
Gene CDX1
Long gene name caudal type homeobox 1
Synonyms gene name caudal type homeo box transcription factor 1
Locus 5q32
Discovery year 1995-05-05
GenBank acession U51095
Entrez gene record 1044
Pubmed identfication 8530027
RefSeq identity NM_001804
Classification HOXL subclass homeoboxes
Havana BLAST/BLAT OTTHUMG00000169772

Subscribe to our Newsletter