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Anti-CHMP2B (Polyclonal), ALEXA Fluor 594

Anti-CHMP2B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCHMP2B
SpecificityThis antibody reacts specifically with CHMP2B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human CHMP2B
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, CHMP2B, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex, Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3), II or III complexes, These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), Widely expressed in brain, also known as CHMP2, and are also required for the formation of these bodies, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins, commonly designated CHMPs, heart, is a 213 amino acid cytosolic protein, lung, pancreas, placenta and leukocytes, skeletal muscle, small intestine, 5 or vacuolar protein-sorting-associated protein 2-2, The charged multivesicular body proteins
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DKFZP564O123 CHMP2, 5 VPS2B
Also known asCHMP2B Polyclonal Antibody
Other nameAnti-CHMP2B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCHMP2B
Short nameAnti-CHMP2B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CHMP2B (polyclonal)
Alternative techniquepolyclonals
Identity 24537
Gene CHMP2B
Long gene name charged multivesicular body protein 2B
Synonyms gene name chromatin modifying protein 2B
Synonyms name VPS2 homolog B (S, cerevisiae)
Locus 3p11, 2
Discovery year 2005-04-04
GenBank acession BC001553
Entrez gene record 25978
Pubmed identfication 11559748
RefSeq identity NM_014043
Classification Charged multivesicular body proteins ESCRT-III
Havana BLAST/BLAT OTTHUMG00000158982

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