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Anti-Chondroitin sulfate proteoglycan NG2, ALEXA Fluor 594

Anti-Chondroitin sulfate proteoglycan NG2, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideChondroitin sulfate proteoglycan NG2
SpecificityThis antibody reacts specifically with Chondroitin sulfate proteoglycan NG2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human Chondroitin sulfate proteoglycan NG2
Gene ID1464
Swiss ProtQ6UVK1
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ACK1 and BCAR1, Binds through its extracellular N-terminus growth factors, Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate, Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins, May activate FAK and ERK1/ERK2 signaling cascades, May also inhibit neurite outgrowth and growth cone collapse during axon regeneration, May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin, May promote retraction fiber formation and cell polarization through Rho GTPase activation, May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties, May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, extracellular matrix proteases modulating their activity, Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NG2 G16 RING5 RMA1
Also known asChondroitin sulfate proteoglycan NG2 Antibody
Other nameAnti-Chondroitin sulfate proteoglycan NG2
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetChondroitin sulfate proteoglycan NG2
Short name Fluor 594, Anti-Chondroitin sulfate proteoglycan NG2
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Chondroitin sulfate proteoglycan NG2
Identity 10068
Gene RNF5
Long gene name ring finger protein 5
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein 5
Locus 6p21, 32
Discovery year 1997-10-16
GenBank acession U89336
Entrez gene record 6048
Pubmed identfication 9533025
RefSeq identity NM_006913
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000031093

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