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Anti-CHRDL1 (Polyclonal), ALEXA Fluor 594

Anti-CHRDL1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCHRDL1
SpecificityThis antibody reacts specifically with CHRDL1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from human CHRDL1
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Additionally, CHRDL1 (Chordin-like protein 1), CHRDL1 binds to BMP-4 and prevents the interaction of BMP-4 with its target receptors, CHRDL1 is thought to play a role in dorsoventral axis formation, Chordin is a key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like BMPs and sequestering them in latent complexes, Functioning in a similar manner to chordin, VOPT (Ventroptin) or NRLN1 (Neuralin-1), Wnt proteins and BMPs (bone morphogenetic proteins), also known as CHL, as well as in the differentiation of neural stem cells, embryonic bone formation and angiogenesis, including Shh (sonic hedgehog homolog), is a 450 amino acid secreted protein that contains three VWFC domains, namely chordin and Noggin, thereby antagonizing BMP-4 activity, with their antagonists, The patterning of the central nervous system (CNS) relies on the interaction of multiple signaling molecules
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NRLN1 CHL
Also known asCHRDL1 Polyclonal Antibody
Other nameAnti-CHRDL1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCHRDL1
Short nameAnti-CHRDL1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CHRDL1 (polyclonal)
Alternative techniquepolyclonals
Identity 29861
Gene CHRDL1
Long gene name chordin like 1
Synonyms gene MGC1
Synonyms gene name megalocornea 1 (X-linked)
Locus Xq23
Discovery year 2004-01-28
GenBank acession AL049176
Entrez gene record 91851
Pubmed identfication 11441185 11118896 22284829
RefSeq identity NM_145234
Havana BLAST/BLAT OTTHUMG00000022199
Locus Specific Databases Mental Retardation database

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