Name : Anti-CHRNA10 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5269748752
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | CHRNA10 |
| Specificity | This antibody reacts specifically with CHRNA10 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human CHRNA10 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | ACh Ralpha 10, AChR alpha 10 forms a hetero-oligomeric channels in conjunction with AChR alpha 9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli, Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system, Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, These transmembrane receptors change conformation in response to their cognate neurotransmitter, Two important members of this family are the nicotinic acetylcholine and glutamate receptors, allowing ions to move through the pore, also known as CHRNA10, an enzyme that rapidly hydrolyzes acetylcholine, both of which are composed of five homologous subunits forming a transmembrane aqueous pore, cultured T-cells and peripheral blood lymphocytes, immortalized B-cells, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Also known as | CHRNA10 Polyclonal Antibody |
| Other name | Anti-CHRNA10 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | CHRNA10 |
| Short name | Anti-CHRNA10 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-CHRNA10 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 13800 |
| Gene | CHRNA10 |
| Long gene name | cholinergic receptor nicotinic alpha 10 subunit |
| Synonyms gene name | alpha 10 (neuronal) cholinergic receptor, alpha polypeptide 10 cholinergic receptor, cholinergic receptor, nicotinic, nicotinic, nicotinic alpha 10 |
| Synonyms name | acetylcholine receptor, alpha 10 (neuronal) , nicotinic |
| Locus | 11p15, 4 |
| Discovery year | 2000-11-28 |
| GenBank acession | AF199235 |
| Entrez gene record | 57053 |
| Classification | Cholinergic receptors nicotinic subunits |
| Havana BLAST/BLAT | OTTHUMG00000011844 |