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Anti-CHRNA10 (Polyclonal), ALEXA Fluor 594

Anti-CHRNA10 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideCHRNA10
SpecificityThis antibody reacts specifically with CHRNA10
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human CHRNA10
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information ACh Ralpha 10, AChR alpha 10 forms a hetero-oligomeric channels in conjunction with AChR alpha 9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli, Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system, Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, These transmembrane receptors change conformation in response to their cognate neurotransmitter, Two important members of this family are the nicotinic acetylcholine and glutamate receptors, allowing ions to move through the pore, also known as CHRNA10, an enzyme that rapidly hydrolyzes acetylcholine, both of which are composed of five homologous subunits forming a transmembrane aqueous pore, cultured T-cells and peripheral blood lymphocytes, immortalized B-cells, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asCHRNA10 Polyclonal Antibody
Other nameAnti-CHRNA10 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetCHRNA10
Short nameAnti-CHRNA10 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-CHRNA10 (polyclonal)
Alternative techniquepolyclonals
Identity 13800
Gene CHRNA10
Long gene name cholinergic receptor nicotinic alpha 10 subunit
Synonyms gene name alpha 10 (neuronal) cholinergic receptor, alpha polypeptide 10 cholinergic receptor, cholinergic receptor, nicotinic, nicotinic, nicotinic alpha 10
Synonyms name acetylcholine receptor, alpha 10 (neuronal) , nicotinic
Locus 11p15, 4
Discovery year 2000-11-28
GenBank acession AF199235
Entrez gene record 57053
Classification Cholinergic receptors nicotinic subunits
Havana BLAST/BLAT OTTHUMG00000011844

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